![]() ![]() 3,4 The at-home utilization of these devices also increases the risks of complications associated with patient errors in their appropriate care and management. Prolonged catheter placement can cause numerous complications, including infection, thrombosis, and device dysfunction. However, the clinically stable patient may benefit from partial or complete oral antibiotics by improving their mobility, reducing the risk of IV catheter–related infections and discomfort, as well as reducing healthcare costs. This mantra is indeed warranted in acutely ill patients, such as those with sepsis, as timely IV antibiotics can be lifesaving. 1 IV antibiotics are generally thought to be the mainstay of treatment for BSIs with their high bioavailability and fast peak plasma levels. Oral therapy offers several benefits with similar outcomes, and the decision to treat a patient with oral antibiotics should be based on current evidence as well as patient, pathogen, and drug characteristics.īacterial bloodstream infections (BSIs) are a considerable cause of morbidity and mortality, with nearly 30 million cases worldwide each year resulting in 6 million deaths and insurmountable costs. Associated costs and risks with IV agents make them less than ideal in many infectious diseases, including bacteremia. ![]() However, the ideal route of administration of any medication is one that achieves serum concentrations sufficient to produce the desired result without any unwanted effects. ABSTRACT: IV antibiotics are generally thought to be the mainstay of treatment for bloodstream infections due to their high bioavailability and fast peak plasma levels. ![]()
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